Thursday, August 4, 2016
I was just studying David Goodsell's paper Miniseries: Illustrating the Machinery of Life - Escherichia coli (http://onlinelibrary.wiley.com/doi/10.1002/bmb.20345/full - do yourself an enormous service and check it out!). I've reserved Thursdays for doing publication stuff - reading, writing, etc. I figured since David's paper is basically what I'm trying to do, I should get intimately familiar with it. Wow! I learned a lot! Especially interesting was the existence of SMC proteins (Structural Maintenance of Chromosomes). Right in the middle of his illustration was MukBEF, an enromous, star-like structure that I had never noticed before. Turns out these guys are important for condensing DNA. I had never even thought about this before! This is truly the great thing (one of the great things) about this work - it leads me to insights that I might never make without it. Thanks, David, for opening my eyes yet again!!! :)
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WOW!! Tell me what you're trying to do that is in Goodsell's paper. You explained the stuff so well I can ALMOST understand it :-) Please send me more.
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